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Chronic Obstructive Pulmonary Disease Drug(Pd No. : 3078673)

(Updated : Feb/06/2017)
product information
Model Nm
HS CODE 300490
M.O.Q
Ceritification
Keywords Yungjin Pharm, Chronic Obstructive Pulmonary Disease Drug, Respiratory Disease
Seller ID narakang1
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US FDA Phase 2a Completion and KFDA Phase 2b Approval of YPL-001

(Chronic Obstructive Pulmonary Disease Drug)



[Development and Market Objectives]


YPL-001 is a natural product developed by Yungjin pharm for COPD treatment. It is the 1st Koran natural products with phase I IND approved by FDA and has been government funded project since 2011. Phase IIa is undergoing in 4 USA hospitals now and we are looking for licensing out partners or co-development partner after phase IIa.



[Unmet Medical Need & Target Patients]


Unmet Medical Needs

Efficacy

- The primary unmet medical need of COPD is to find a treatment preventing the disease progression from stage 2 or 3 to stage 3or 4


• Steroid sensitivity

- COPD patients have a tendency of reduced responsiveness to steroids as their disease progresses. So symptoms get worse even using steroids especially for stage 3 or 4 patients. Thus, to reduce corticosteroid resistance in patients is important in acute or frequent COPD exacerbations.


• Safety

- COPD requires long-term treatment. Most of existing treatments for COPD have safety issues. Development of product with less side effects is needed. • 


• Formulation

- Most COPD drugs are inhalant type which need patient education for usage. Oral dosage form is easy and convenient for dosing, usually cheaper than device type drug which is helpful especially in underdeveloped country.



[Target patients]


COPD patients are classified based on their degree of severity - Mild (Stage 1), Moderate (Stage 2), Severe (Stage 3), Very severe (Stage 4). The ultimate and primary goal of treatments is to prevent exacerbation of COPD. For such purpose, long term safety and prevention the development of resistance should be secured. None of the existing

drugs have been proven to stop the disease progression from Stage 1 or 2 to Stage 3 or 4. YPL-001 is for stage 2 or 3 patients to prevent COPD exacerbation.



[Status]


Yungjin has completed Phase 1a (Single Ascending Dose Study) and 1b study (Multiple Ascending Dose Study). The IND and IRB have been done for Phase IIa and currently patients recruiting are ongoing.



[Intellectual Property]


Patent registered: total 17 patents completed

- Korea(4), USA(2), Europe(6), Japan(1), China(1), India(1),

Canada(1), Australia(1)


Patent pending: Korea(1), US(1), PCT(2)

- Covering worldwide



[Competitive Advantages]


Unique MoA

- Reduce inflammatory response and increase steroid sensitivity as HDAC2 activator (First In Class) 


• Well- controlled CMC

- Phytoequivalence established

- Identified components (> 90 % (w/w)) - Standardized API by GAP*


• Formulation

- Oral dosage form: easy compliance compared to inhalants


• Exclusivity

- Well protected intellectual property through several patent application



Company Information

company information
Contact Person Na Ra Kang
Company Yungjin Pharm. Co., Ltd
Address
Homepage www.yungjin.co.kr , http://seller.buykorea.org/yungjin-pharm--1040488
Tel . Fax
Biz. Type Est. Year
Employees Annual Export USD 0~1 mn
Related Business Event List
Global Bio Pharma Plaza(GBPP 2017) 2017-11-27 ~ 2017-11-28
Innovation & Technology Business Partnering 2017 COEX Intercontinental, Seoul, South Korea 2017-03-29 ~ 2017-03-30
CPhI World Wide 2016 2017-10-24 ~ 2017-10-26
InnoMedi 2017-03-29 ~ 2017-03-29
Int’l Pharmaceutical Ingredients Expo & Conference 2017 2017-06-28 ~ 2017-06-30
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